At present, only a handful of clinicians have been formally trained to administer psilocybin, all in university research projects, and none of them are in Colorado or Oregon.

George Greer

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In the right circumstances, MDMA reduces or sometimes eliminates the neurophysiological fear response to a perceived threat to one's emotional integrity... With a barrier of fear removed, a loving and forgiving awareness seemed to occur quite naturally and spontaneously.

drug emotional integrity

Additionally, a small portion of people have histories of psychotic or manic episodes, and psilocybin could worsen those conditions or trigger a relapse.

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