In the new monthly dosing trials...the mean percent reduction in LDL-C from baseline was consistent with that seen in previous phase 3 trials evaluating alirocumab every other week dosing. Bill Sasiela More Quotes by Bill Sasiela More Quotes From Bill Sasiela This is the first time a PCSK9 inhibitor has shown in a clinical study that it reduced the frequency of apheresis therapy, an invasive, difficult to access, time-consuming and expensive treatment for some of the most difficult-to-treat patients. Bill Sasiela health-news