The evolvement of proteolysis as a centrally important regulatory mechanism is a remarkable example for the development of a novel biological concept and the accompanying battles to change paradigms. Aaron Ciechanover More Quotes by Aaron Ciechanover More Quotes From Aaron Ciechanover We didn't come to criticize them, we didn't come to ask about the meaning of democracy in their eyes, we really came to converse and to exchange dialogue with students. Aaron Ciechanover world Biochemistry is the science of life. All our life processes - walking, talking, moving, feeding - are essentially chemical reactions. So biochemistry is actually the chemistry of life, and it's supremely interesting. Aaron Ciechanover walking life science moving Reticulocytes are terminally differentiating red blood cells that do not contain lysosome. Therefore, it was postulated that the degradation of hemoglobin in these cells is mediated by a non-lysosomal machinery. Aaron Ciechanover therefore red cells blood We are a country that lacks riches. The Jewish brain, that's what we have. Everything that we've had and will have in this country is the direct and clear product of higher education. If we harm this system, we will drastically decline and cease to exist. Aaron Ciechanover will education brain country My brother Joseph, who is 14 years older than me, was already on his national military compulsory service when I was 4 years old, the age from which I remember myself. Aaron Ciechanover myself me brother age I grew up in Haifa and enjoyed the wonderful beaches and Mount Carmel that rolls into the Mediterranean Sea. From my early days at home, I remember a strong encouragement to study. Aaron Ciechanover strong sea home remember My father left me with his love of Jewish studies and cultural life. To this very day, along with several physicians and scientist colleagues, I take regular periodical lessons taught by a Rabbinical scholar on how the Jewish law views moral and ethical problems related to modern medicine and science. Aaron Ciechanover day me love life Towards the end of the military service, I had to make what I assume has been the most important decision in my career: to start a residency in clinical medicine, in surgery, which was my favorite choice, or to enroll into graduate school and start a career in scientific research. It was clear to me that I was heading for graduate school. Aaron Ciechanover me service decision school The problem of different sensitivities of distinct protein groups to lysosomal inhibitors has remained unsolved and may have served as an important trigger in the future quest for a non-lysosomal proteolytic system that may be involved in at least certain aspects of intracellular protein degradation. Aaron Ciechanover future different important problem The development of methods to monitor protein dynamics in cells together with the discovery of specific and general lysosomal inhibitors have resulted in the identification of different classes of cellular proteins, long- and short-lived, and the findings of the differential effects of the inhibitors on these groups. Aaron Ciechanover different development together long To develop drugs for people, we basically dismantle the system. In the lab, we look at things the size of a cell or two. We dismantle life into very small models. Aaron Ciechanover small look life people We discovered a mechanism which is like the garbage machine of the body. We need to remove damaged proteins and create new ones in their place, and we discovered the machine that does this. Aaron Ciechanover new place garbage body The important thing is to do what you most love in the best way. If you love literature, you could be a great writer and perhaps one day become a Nobel Prize Laureate for Literature. Aaron Ciechanover best day you love The chances of Israeli science competing with big American science are small. For almost 15 years, we had no competition. Aaron Ciechanover small big competition science The scale of time for a politician runs between one primary and the next, and in Israel, this means two to three years because elections almost never take place once every four years as stipulated by law. The timetable for a system of research is completely different. Aaron Ciechanover place research law time We need to save the education system. We need to remove education from the framework of the political parties that rule in the State of Israel. We need to increase the allocation of long-term national resources to education and never touch them - no matter what. Aaron Ciechanover never political matter education Bringing together the unique expertise of researchers from both NYU and the Technion will hopefully enable us to overcome some of the most difficult challenges in treating cancer patients. Aaron Ciechanover will unique challenges together I studied at the Hebrew University Medical Faculty, graduated, and was an Israel Defense Forces' combat physician on a Navy ship. Aaron Ciechanover ship university navy medical I went to the Technion and studied with Avram Hershko. I found it more exciting than practicing medicine. Aaron Ciechanover than more medicine found I try hope that in the end, we will live in a cancer-free world. We want to live disease-free lives. Aaron Ciechanover live end hope world
