There’s always concern when we’re intervening at this level. But the great majority of data suggest that ICSI is a very safe procedure. Thomas Molinaro More Quotes by Thomas Molinaro More Quotes From Thomas Molinaro One of the hallmarks of a good center is that they’re willing to adopt to new technologies. Thomas Molinaro health You see a center who has high success rates but their average embryo transfer is 2.5 and they have 40 to 50 percent twins— they’re not doing a good job of selecting embryos appropriately. Thomas Molinaro health The question has always been and still sort of remains is : Is it ICSI itself which leads to this increased risk or is it the patient who needs ICSI ? iCSI overcomes many sperm problems but it does n’t overcome all problems. Thomas Molinaro health For the most part, it’s rare that we have good outcomes after failed fertilization. Thomas Molinaro health When we biopsy the embryo for testing, this residual sperm can create interference which affects the fidelity of the testing. Using ICSI removes this contamination and results in better accuracy. Thomas Molinaro health