Within one year of starting work, I had found that the nucleus of an endoderm cell from an advanced tadpole was able to yield some normal development up to the nuclear transplant tadpole stage. John Gurdon More Quotes by John Gurdon More Quotes From John Gurdon I must have been born with a strong attraction toward, and possibly even an aptitude for, doing things on a small scale. John Gurdon doing small born strong I remember that, at an early age, I spent many months making a three-masted sailing boat with rigging in a half-walnut shell. John Gurdon early boat age remember My first attempts to transplant nuclei in Xenopus were completely unsuccessful, because the Xenopus egg, unlike those of other amphibians, is surrounded by an extremely elastic membrane and jelly layer that make penetration by a micropipette impossible. John Gurdon surrounded egg first impossible Within six months of starting my Ph.D. work in 1956, I had already obtained feeding tadpoles derived from transplanted nuclei of embryonic cells. John Gurdon feeding starting cells work In principle. what is done is to take the nucleus out of a cell with a very fine micro-pipette or needle and introduce it into an egg. That had been done with amphibians a long time ago, and then there was a long pause of many years before people were clever enough to make that work in the sheep. John Gurdon work time long people