Jacques Guyette

Regenerating a whole heart is most certainly a long-term goal that is several years away, so we are currently working on engineering a functional myocardial patch that could replace cardiac tissue damaged due to a heart attack or failure, among the next steps that we are pursuing are improving methods to generate even more cardiac cells— recellularizing a whole heart would take tens of billions— optimizing bioreactor-based culture techniques to improve the maturation and function of engineered cardiac tissue, and electronically integrating regenerated tissue to function within the recipient’s heart.

Jacques Guyette