It has since become clear that these interventions to reduce estrogen levels weren’t effective, and we haven’t been doing them anymore. Robert Kotloff More Quotes by Robert Kotloff More Quotes From Robert Kotloff Women with LAM who become pregnant often experience an acute worsening of their disease, and women who take estrogen therapeutically in birth control pills or in the past with hormonal supplementation for menopausal women, we saw LAM would accelerate in [those groups]. Robert Kotloff health We now view LAM in essence as a malignancy but one that progresses over years, not days or months like cancer. Robert Kotloff health There were rare instances of women whose lung function improved significantly, but most improved with stabilization. Robert Kotloff health